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Xpert® SA Nasal Complete

Pre-surgical testing of S. aureus and MRSA in about an hour

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Xpert<sup>®</sup> SA Nasal Complete
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VIDEO

Catawba Valley Medical Center leverage the GeneXpert® for HAI Testing

Catawba Valley Medical Center, a non-profit, locally controlled community hospital in Hickory North Carolina highlights how they utilize the GeneXpert System throughout the hospital to improve patient care.

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The Need

Staphylococcus aureus infections are an increasingly serious public health issue.

Colonized patients at risk for serious complications include surgical, trauma, burn and dialysis patients:

  • S. aureus colonized patients are up to 9 times more likely to develop surgical site infections than non-carriers1
  • S. aureus is the major cause of access infections and bacteremia in dialysis patients2
  • Carriage is the major risk factor for infection with S. aureus in dialysis patients4
  • Up to 93% of nosocomial S. aureus infections are caused by a patient’s own flora3,4
  • SA and MRSA infections are associated with increases in length of hospital stay, costs, morbidity, and mortality6,7,11
  • Nasal carriage of S. aureus and self-infection of wounds in ICU/Burn patients is well documented9,10

The Solution

Rapid and accurate detection of colonization facilitates targeted infection control practices:

  • Optimize pre-admission workflow and counseling
  • Enables measures to reduce endogenous infection risk, including decolonization
  • Supports measures to reduced exogenous infection risk, including barrier/contact precautions
  • Aligns with infection control strategies as outlined by SCIP and SHEA/IDSA

The Impact

Surgical Site Infections (SSIs) due to SA & MRSA significantly increase risk of death, costs and hospitalization as compared to surgeries without SSIs.6,7

 

Rapid detection and implementation of targeted control measures improves your bottom line by reducing adverse medical care events. Hospitals absorb most of the costs for adverse medical care events.

(1) Kluytmans J, et al. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev. 1997 Jul;10(3):505-20.
(2) Piraino B. Staphylococcus aureus infections in dialysis patients: focus on prevention. ASAIO J. 2000 Nov-Dec;46(6):S13-7.
(3) Critchley IA. Eradication of MRSA nasal colonization as a strategy for infection prevention. Drug Discov. Today. 2006;3(2):189-95.
(4) Yu VL, et al. Staphylococcus aureus nasal carriage and infection in patients on hemodialysis. Efficacy of antibiotic prophylaxis. N Engl J Med. 1986 Jul 10;315(2):91-6.
(5) Murphy D, et al. Dispelling the Myths: The True Cost of Healthcare-Associated Infections. An APIC Briefing. 2007 Feb. Accessed May 2020. http://www.thainapci.org/download-guideline-6.pdf/
(6) Engemann JJ, et al. Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection. Clin Infect Dis. 2003 Mar 1;36(5):592-8. Epub 2003 Feb 7.
(7) Anderson, DJ. Clinical and Financial Outcomes Due to Methicillin Resistant Staphylococcus aureus Surgical Site Infection: A Multi-Center Matched Outcomes Study. PLOS One. 2009 Dec 15. Accessed May 2020. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008305
(8) Bode LG, et al. Preventing Surgical-Site Infections in Nasal Carriers of Staphylococcus aureus. N Engl J Med. 2010 Jan 7;362:9-17.
(9) Mackie DP, et al. Reduction in Staphylococcus aureus wound colonization using nasal mupirocin and selective decontamination of the digestive tract in extensive burns. Burns. 1994;20 Suppl 1:S14-7; discussion S17-8.
(10) Kooistra-Smid M, et al. Molecular epidemiology of Staphylococcus aureus colonization in a burn center. Burns. 2004 Feb;30(1):27-33.
(11) Noskin GA, et al. The Burden of Staphylococcus aureus Infections on Hospitals in the United States. Arch Intern Med.2005;165(15):1756–1761.

Ordering Info

Xpert® SA Nasal Complete

Number of Tests: 10

Catalog #: GXSACOMP-10

Educational Materials

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Limiting Inappropriate Antibiotic Use in the ED
VIDEO

Limiting Inappropriate Antibiotic Use in the ED

Dr. Larissa May discusses how clinical practice guidelines on skin and soft tissue infections make it more important than ever to use diagnostics to guide targeted antibiotic use. Hear how her institution was able to reduce inappropriate antibiotic use in the ED with the help of on-demand PCR testing for MRSA and S. aureus.

Meet our Game-Changing Platform
VIDEO

Meet our Game-Changing Platform

With over 36,000 installed systems worldwide, the GeneXpert System is the most popular sample-to-answer PCR testing system. See how it’s helping clinicians everywhere make a more positive impact.

Benefits of Presurgical MRSA/S. aureus Testing
WEBINAR

Benefits of Presurgical MRSA/S. aureus Testing

White Paper: Supporting CDC’s Four Core Actions to Fight Antimicrobial Resistance
DOCUMENT

White Paper: Supporting CDC’s Four Core Actions to Fight Antimicrobial Resistance

CDC has declared the complex problem of AMR a serious threat today, which will result in potential catastrophic consequences with continued inaction. To combat AMR, the CDC has identified 4 core actions, all of which can be addressed through rapid molecular diagnostics:

Antibiotic Stewardship in the Emergency Department
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Antibiotic Stewardship in the Emergency Department

This webinar discusses the importance of diligent antimicrobial stewardship and accuracy of diagnostic tests for the detection of Group A Streptococcus pharyngitis. It provides commentary on the high confidence that molecular testing affords the antibiotic steward and how technology can reduce the practice of prescribing antibiotics "just-in-case" there is an infection, especially as testing moves closer to the patient.

RDT+ASP: How New Rapid Diagnostics are Supercharging Antimicrobial Stewardship Programs
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RDT+ASP: How New Rapid Diagnostics are Supercharging Antimicrobial Stewardship Programs

This webinar discusses data supporting the combination of rapid diagnostic tests (RDT) and antimicrobial stewardship programs (ASPs), reviews RDT systems, and provides guidance on how ASPs can implement and optimize the use of RDTs in virtually any healthcare setting.

Ephraim McDowell Regional Medical Center
DOCUMENT

Ephraim McDowell Regional Medical Center

Ephraim McDowell Regional Medical Center improves adherence to optimized testing protocols for C. difficile resulting in lower C. difficile rates and decreased patient time in isolation.    

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